Innovation

Organization

Fields

New Immunostimulants as Vaccine Adjuvants and Drugs for the Immunotherapy of Cancer and Infectious Diseases

This invention presents novel conjugated compounds that act as dual agonists of TLR7 and NOD2, offering potent immunostimulatory effects for the treatment of infections, tumors, and immunological diseases, as well as for use as vaccine adjuvants, with the unique advantage of synergistically enhancing immune responses through simultaneous activation of both

Design of a bilayer mucoadhesive film for the delivery of vaccines or nucleic acid-based therapeutics

Nucleic acid-based therapies are delivered using different methods. COVID-19 vaccines are typically injected into muscles, but they pose challenges such as weak mucosal immunity. Conversely, mucosal vaccines delivered orally or intranasally offer better compliance and fewer side effects, but face problems like inconsistent absorption. Mucoadhesive films may enhance the delivery